Planning car hire in Frosinone, a town in Lazio, central Italy, allows you to explore the Lazio region to your heart'’s content. Visit our Frosinone branch and let us see what we can do for you. Frosinone sits on a hill, overlooking the valley of the Sacco River, which really opens up the region of Ciociaria to your driving delight. Frosinone is only one hour and four minutes from Rome, Italy’'s capital and centre of so much history, whether you are interested in ancient Roman history at the coliseum, the interest provoked by the independent Catholic powerhouse of the Vatican, or the artistic beauty which adorns the walls of the Sistine Chapel.